The rtvue has several unique features encompassing imaging and analysis and technological capability. The vessel density vd was measured using an rtvue xr with angiovue. These axons are distributed in an organized pattern from the soma of the rgc to the lateral geniculated nucleus where most of the neurons synapse. Apr 12, 2011 making the most of anterior segment oct the detailed images produced by this technology are proving to be of value in many clinical situations. Novice clinicians were more accurate in correctly determining that a lesion was not an ossn ruling it out as a diagnosis than in determining that a lesion was an.
Research article open access comparison of vascular parameters between normal cynomolgus macaques and healthy humans by optical coherence tomography angiography. The second edition of oct and imaging in central nervous system diseases offers updated stateoftheart advances using optical coherence tomography oct regrading neuronal loss within the retina. Glaucoma is obviously an important part of this book, but one part is. Visual field vf, spectralis rnfl 83 patients and 37 healthy subjects and rtvue rnfl data obtained separately 56. Provides key feature points for each disorder giving you the needtoknow oct essentials for quick comprehension and rapid reference. We also observed that sdoctderived measurements of cct tended to be thinner than with the schiempflug camera. Ophthalmic imaging is an integral part of the work of all ophthalmic departments. Discuss glaucoma diagnosis and progression in terms of oct 2. The texts primary objective is to illustrate the appearance of the eye in health and disease, comparing conventional clinical technologies using spectral domain oct imaging.
The content of this book presents the viewpoint of the author and do not necessarily. Guide to interpreting spectral domain oct by patty seiden issuu. Atlas and clinical reference guide for corneal topography. With handbook of retinal oct, you can master the latest imaging methods used to evaluate retinal disease, uveitis, and optic nerve disorders. The main objective of this investigation was to compare. Shallow introduction for deep learning retinal image analysis. Detailed information on the oct imaging and interpretation is provided for the evaluation of disease progression in numerous neurodegenerative. Jun 10, 2010 guide to interpreting spectral domain oct a stepbystep guide for interpreting images and data using cirrus hd oct. It reaches both retinal specialists and general ophthalmologists with practical insight. Jan 04, 2018 early detection, monitoring and understanding of changes in the retina are central to the diagnosis of glaucomatous optic neuropathy, and vital to reduce visual loss from this progressive condition. Reproducibility of central corneal thickness measurements. Optical coherence tomography oct is a noninvasive imaging technique. This is part of the spectral domain oct interpretation for the general ophthalmologist series, which focuses on use of sdoct in patients with glaucoma and retinal disease.
Sep 15, 2015 the anatomy of an oct scan octsand their printoutscan be tough to understand. To estimate the floor of retinal nerve fibre layer rnfl thickness measurements and the corresponding retinal sensitivity loss in glaucoma. In followups, progression analysis by rtvue compares the rnfl thickness measurements and the gcc map over time and thus, determines whether statistically. This open access book provides a comprehensive overview of the application of. Detection of disease progression is an important and challenging component of glaucoma management. An understanding of the underlying principles for a specific imaging technology is essential for accurate data interpretation, especially since noncontact cct measurement devices are potentially more practical to employ in a busy clinical practice. Interpretation of oct american academy of ophthalmology. Optical coherence tomography angiography octa is a new, noninvasive imaging technique that generates volumetric angiography images in a matter of seconds. Oct 27, 2016 recipes and stories from a modern diner. Making the most of anterior segment oct the detailed images produced by this technology are proving to be of value in many clinical situations. Clinical experience with fourier domain oct retina today.
Michael deiner 27 ucsf department of ophthalmology. A total of 109 eyes from 59 subjects were scanned with two sdoct devices cirrus and rtvue at the same visit. With its high resolution and proven measurement reproducibility. Viewers are given an overview of scanning protocols on various sd oct systems as lecturers present an organized method for analysis of images and identification of pathology. At present, level 1 evidence of the technologys clinical applications doesnt exist. King the divinity school, harvard university, cambridge, ma 028 email. The rtvue offers comprehensive glaucoma evaluation by providing assessment of the rnfl thickness, optic disc morphology, and the ganglion cell complex thickness. What you need to convert a oct file to a pdf file or how you can create a pdf version from your oct file. This is an open access article published by world scientific publishing company. Shallow introduction for deep learning retinal image analysis 1. The normal left eye of a 56 year old caucasian man using the angiovue optical coherence tomography angiography octa software of the rtvue xr avanti optovue, inc. Retinal thickness in black and indian myopic students at. The use of spectral domain optical coherence tomography sdoct technology has enabled clinicians to obtain highresolution images of the optic nerve head onh, rnfl and macular regions. Clinical use of oct in assessing glaucoma progression.
The oct image 7 normal retina and key retinal pathologies. The introduction of spectraldomain oct sd oct has allowed objective quantification of damage. The first chapter concerns the principles and interpretation of oct and has a purely practical function, to help the reader understand the results. A 20minute instructional lecture was given on hr oct interpretation, and the same 26 images were shown. Oct angiogram fields of view and segmentation layers on angiovue. Direct ganglion cell assessment with the rtvue 3 optovue oct. Zeiss have agreed to write, publish and distribute this book free of charge. A quantitative and qualitative approach examining the three. Guide to interpreting spectral domain oct by patty seiden. The place of the gospel of philip in the context of early christian claims about jesuss marital status karen l. Environews, october 2005 3 news flash water prize for sunita m narain s. It thus provides a flow map with depthresolved visualization of the various vascular layers in the posterior pole of the eye including the retina capillary plexus and the choroid.
It reaches both retinal specialists and general ophthalmologists with practical insight regarding current and future treatment strategies. Oct in glaucoma diagnosis, detection and screening intechopen. Request pdf on jan 1, 2015, david huang and others published chapter02 interpretation of optical coherence tomography angiography find, read and cite all the research you need on researchgate. Heres a howto on differentiating oct models and reading their scans. Advances in oct have made it a useful diagnostic tool in ethambutol toxicity, hydroxychloroquine retinopathy, optic nerve head drusen, glaucoma, idiopathic intracranial hypertension, and multiple sclerosis, to name a few conditions. Spectraldomain optical coherence tomography for glaucoma. This monograph aims to give an update on the use of oct in glaucoma and pathologies of the optic nerve. Add it all up and you arrive at an unparalleled combination of ease and clinical utility that makes the iseries the best value in octwhich leads to optimum eye health for your patients.
Oct in glaucoma and pathologies of the optic nerve. Nov 26, 2018 ophthalmic surgery, lasers and imaging retina. Influence of axial length on peripapillary retinal nerve fiber layer thickness in children. Twentysix blackandwhite hr oct images were projected, and clinicians were asked to determine whether the lesions represented ocular surface squamous neoplasia ossn or another ocular surface pathology. Huang has coauthored several books on anterior segment oct, including anterior segment optical coherence tomography and imaging the eye from front to back with rtvue fourierdomain optical coherence tomography. A pdf printer is a virtual printer which you can use like any other printer. Optical coherence tomography angiography octa employs a novel imaging algorithm that detects the amplitude or phase decorrelation of blood cell movement. The mean frequency of correct identification of the 26 lesions was 70% standard deviation sd 15% before instruction. Pearls and pitfalls of optical coherence tomography. Aug 20, 2016 shallow introduction for deep learning retinal image analysis 1. Macular thickness maps may also be helpful in making the diagnosis of nonglaucomatous optic neuropathies. Reproducibility of central corneal thickness measurements in. Glaucoma is a multifactorial optic neuropathy characterized by a loss.
Macular thickness analysis for glaucoma diagnosis and management. The module also offers angletoangle imaging for efficient anterior chamber angle evaluation. Optical coherence tomography oct has proved to be valuable in the detection of glaucomatous damage. The analysis report varies with different oct systems. Home ophthalmology books oct in central nervous system diseases. Viewers are given an overview of scanning protocols on various sdoct systems as lecturers present an organized method for analysis of images and identification of pathology. The avanti embodies many of the firsts in sdoct development that optovue has introduced to eye care. The evaluation and comparison of macular and optic disc vascular circulation parameters between normal adult cynomolgus macaques and healthy adult humans using oct a can promote better use of nonhuman primate models in studies of.
Chapter02 interpretation of optical coherence tomography. Domainspecific issues sparse convnets compressed sensing feature. This is part of the spectral domain oct interpretation for the general ophthalmologist series, which focuses on use of sd oct in patients with glaucoma and retinal disease. The authors suggested that the rtvue oct appeared to report more accurate, but thinner cct measurements, than the oculyzer 2. Optical coherence tomography spectral domain oct interpretation case series. Comparison of zeiss cirrus and optovue rtvue oct angiography. Sunita narain, noted environmental scientist and director of delhibased centre for science and environment cse, has been honoured with the 2005 stockholm water prize. Further distribution of this work is permitted, provided the original work is properly cited. The first chapter covers the basic principles and interpretation of oct and is intended to help the reader interpret oct images. Another advantage of the iseries systems is completeness, the capacity for one oct to deliver the full spectrum of applications from retina to cornea. The optic nerve on is constituted by the axons of the retinal ganglion cells rgcs. Repeatability of cornea and sublayer thickness measurements. Comparison of zeiss cirrus and optovue rtvue oct angiography systems. This is a nascent technology with a potential wide applicability for retinal vascular disease.
Comparison of vascular parameters between normal cynomolgus. Figure 1 shows a cross sectional bscan from the rtvue in the macula region. Oct interpretation jamin brown, md retina vitreous associates of cny december 6th 2014. Participants ages ranged from 18 to 24 years with the mean age of the black and indian participants being 21. The prize has been awarded for efforts made by cse in fighting powerful, topdown bureaucratic resource. Cynomolgus macaques is widely used in ophthalmic disease research. The key points of the on are the optic nerve head and chiasm.
When he noticed that rudy was holding a bat, he came toward. Oct is a well known and frequently used technology to image the posterior segment. Optical coherence tomography for glaucoma diagnosis. Optical coherence tomography, by the same expert author team of drs. The preliminary statistical analysis revealed that macular retinal thickness measurements of the right and left eyes showed significantly high levels of symmetry. Sep 10, 2019 optical coherence tomography oct is a noninvasive imaging technique. Summarize research about oct related to diagnosis and progression 4. The rtvue sdoct system was launched in 2006 with fast retina mapping. Posterior vitreous detachment is typically a nonpathologic agerelated event. It is distributed under the terms of the creative commons attribution 4. Provide tips for better oct analysis in clinical practice. Anomalous posterior vitreous detachment emerges when the vitreous cortex fails to cleanly detach from the macula, optic nerve, or other adherent sites.
Detailed information on the oct imaging and interpretation is provided for. Oct technology generates highresolution, crosssectional and threedimensional 3d images of the retina, optic disc and anterior segment, to give you valuable information that aids in the diagnosis and management of a range of ocular diseases. Sergott editor this richly illustrated, comprehensive guide will enable the reader to identify anatomy and ophthalmic disease as illustrated on optical coherence tomography oct. Optical coherence tomography has emerged over the years with the ability to detect. Introduction to optical coherence tomography request pdf. This combination has enabled us to bring a fresh perspective to oct, and to create the most innovative, versatile technology available today. Review strengths and weaknesses of oct for glaucoma 3. Coauthor of the first oct clinic paper and book, mit. The cornea is the most external layer of the eye and serves two important roles in 1 the refraction of light and 2 protection from the outside environment, both of which are highly dependent on the collagen assembly of the corneal stroma. Spectralis and cirrus highdefinition oct take the outer most layer, rpe while rtvue takes the inner. The russian soldier came out of the building on the edge of the baseball field, holding a ball on his hand. All three of these structures are affected in glaucoma. Several studies have been published evaluating the accuracy of different structural measurements obtained with sdoct for diagnosing glaucoma 1923.
Optical coherence tomography oct is a useful adjunct imaging technique for retinal and optic nerve pathology. Ability of novice clinicians to interpret highresolution. The rtvue oct can be helpful to detect glaucomatous damage by quantifying the rnfl thickness, the layers associated with the ganglion cells i. Ideal at any stage of your career, this easytouse, clinically oriented handbook provides a quick, templated, and portable guide for the interpretation of optical coherence tomography scans. Identification of structural damage to the optic nerve and retinal nerve fiber layer rnfl is an essential component of diagnosis and management of glaucoma. No part of this book may be reproduced or transmitted in any form or by any means. To make a correct interpretation of oct measurements, ocular magnification effect should be taken into account by clinicians or oct manufacturers. The evaluation and comparison of macular and optic disc vascular circulation parameters between normal adult cynomolgus macaques and healthy adult humans using octa can promote better use of nonhuman primate. Files of the type oct or files with the file extension. Optical coherence tomography of ocular diseases, third edition is written with the clinician in mind. The use of spectral domain optical coherence tomography sd oct technology has enabled clinicians to obtain highresolution images of the optic nerve head onh, rnfl and macular regions. Several studies have been published evaluating the accuracy of different structural measurements obtained with sd oct for diagnosing glaucoma 1923.
The metabolic activity of retina is higher than other human tissues and is crucial to the vision. He authored more than 190 research publications and edited 17 books on inherited and environmentally induced retinal degenerations. Guide to oct image interpretation with normal and anatomic. Role of optical coherence tomography in the evaluation and. This study sought to determine the collagen fiber arrangement of the canine corneal stroma and correlate the stromal organization with tissue stiffness. Optical coherence tomography has become a powerful tool for analyzing the retina and other ocular structures. A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext. Analysis of current literature regarding oct in diagnosis and management of vitreomacular interface disease. There are normals for ocular structures deviation from the norm abnormality pathology being able to discern differences in reflectivity, morphology and qualitative measures either from normals or from previous scans is the essence of oct interpretation.
Optic nerve head analysis report adapted from carl zeiss oct manual. When he noticed that rudy was holding a bat, he came toward rudy. Authorized translation from the japanese language edition, entitled. Metaanalysis was performed pooling area under the receiver operating characteristic curve auroc estimates for all devices, stratified by oct type rnfl. Therapeutic and surgical treatment of the posterior segment delivers indepth coverage of the latest advances in amd, diabetic retinopathy, macular edema, retinal vein occlusion as well as surgical intervention in posterior segment care. Glaucoma is obviously an important part of this book, but one part is devoted to other eye diseases and especially. Optovue oct has a broad range of applications in todays eye care practices. The authors suggested that the rtvue oct appeared to report more accurate, but thinner cct. Rnfl parameters of the rtvue100 oct have shown high specificity 12. It allows the clinician to record the findings from clinical ocular examination in an objective, reproducible, transmissible and durable manner. An excellent diagnostic companion tohandbook of retinal oct. Designed as both a learning tool for students and a reference for clinicians to use when faced with a challenging topography interpretation, atlas and clinical reference guide for corneal topography will be appreciated by a wide spectrum of eye care professionals. Interpretation of the oct image and some new developments topics. The broad spectrum of application of optical coherence.